**U.S. Route 220**
**Definition**
U.S. Route 220 (US 220) is a north–south United States highway that runs approximately 678 miles from Rockingham, North Carolina, to Waverly, New York.
**Route Description**
US 220 begins in Rockingham, North Carolina, and travels north through Virginia, West Virginia, Maryland, and Pennsylvania before ending in Waverly, New York. The highway serves as a major regional corridor connecting rural and urban areas, passing through cities such as Roanoke, Virginia, and Williamsport, Pennsylvania. It intersects with several major highways, including Interstate 73 in North Carolina and Interstate 99 in Pennsylvania.
**History**
Established in 1926, US 220 has undergone various realignments and upgrades to improve traffic flow and safety. Portions of the route have been expanded to freeway standards, particularly in Pennsylvania and Virginia.
**Significance**
US 220 plays an important role in regional transportation, facilitating commerce and travel across the Appalachian region.
**META_DESCRIPTION**
U.S. Route 220 is a north–south highway running from North Carolina to New York, connecting key cities and serving as a vital regional corridor through the Appalachian region.