**Daniel Alagille**
**Definition:**
Daniel Alagille (1925–2005) was a French pediatrician and hepatologist renowned for his contributions to the study of liver diseases, particularly in children. He is best known for identifying Alagille syndrome, a genetic disorder affecting the liver, heart, and other organs.
**Article**
### Early Life and Education
Daniel Alagille was born in 1925 in France. He pursued medical studies with a focus on pediatrics and hepatology, developing a keen interest in liver diseases affecting children.
### Medical Career
Alagille’s work primarily centered on pediatric liver pathology. Throughout his career, he held various academic and clinical positions, contributing extensively to the understanding of congenital liver disorders.
### Alagille Syndrome
In the 1960s, Daniel Alagille first described a multisystem genetic disorder characterized by bile duct paucity, heart defects, distinctive facial features, and vertebral anomalies. This condition was later named Alagille syndrome in his honor. His research helped establish diagnostic criteria and improved clinical management for affected patients.
### Legacy
Daniel Alagille’s pioneering work has had a lasting impact on pediatric hepatology and genetics. Alagille syndrome remains a significant focus of research and clinical care worldwide.
**Meta Description:**
Daniel Alagille was a French pediatrician known for identifying Alagille syndrome, a genetic disorder affecting multiple organs. His work significantly advanced pediatric liver disease research.