PDXK

Definition: **
PDXK (Pyridoxal Kinase) is an enzyme encoded by the PDXK gene in humans, responsible for the phosphorylation of vitamin B6 vitamers into their active coenzyme forms.

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**PDXK**

**Definition:**
PDXK (Pyridoxal Kinase) is an enzyme encoded by the PDXK gene in humans, responsible for the phosphorylation of vitamin B6 vitamers into their active coenzyme forms.

**Article:**
PDXK plays a crucial role in vitamin B6 metabolism by catalyzing the ATP-dependent phosphorylation of pyridoxal, pyridoxine, and pyridoxamine into pyridoxal 5′-phosphate (PLP), the biologically active form of vitamin B6. PLP serves as a coenzyme in numerous enzymatic reactions, including amino acid metabolism, neurotransmitter synthesis, and hemoglobin function. The PDXK gene is expressed in various tissues, reflecting the widespread necessity of PLP. Mutations or deficiencies in PDXK activity can lead to metabolic disorders related to impaired vitamin B6 utilization.

**Meta Description:**
PDXK is an enzyme essential for activating vitamin B6 by converting it into its coenzyme form, pyridoxal 5′-phosphate. It supports vital metabolic processes in the human body.